Epidural anesthesia with ropivacaine with or without clonidine and postoperative pain in hemorrhoidectomies.

نویسندگان

  • João Florêncio de Abreu Baptista
  • Renato Santiago Gomez
  • Danilo Nagib Salomão Paulo
  • Antonio Roberto Carraretto
  • Marcos Celio Brocco
  • José Jorge Silva
چکیده

PURPOSE To determine the safety, pain intensity correlated with age and body mass index (BMI), epidural anesthesia with ropivacaine and clonidine in hemorrhoidectomy. METHODS Eighty patients, both genders, 20-70 years old, ASA I or II, for hemorrhoidectomy were randomly divided into two groups: Control (n=38), epidural anesthesia with 14 mL of ropivacaine 0.75 % plus 0.0266 mL/kg of 0.9% saline solution; Experimental (n=42) epidural anesthesia with 14 mL of 0.75% ropivacaine plus 4.0 mcg/kg of clonidine. In preoperative and postoperative period were evaluated: systolic blood pressure (SBP), diastolic blood pressure (DBP ), heart rate (HR ), pulse oximetry (SpO2), electrocardiography (ECG), pain intensity (VAS ) in four, eight and, 12 hours and analgesic consumption. RESULTS The VAS values differed between four, eight and 12 hours in the Experimental Group, where correlation of VAS 12h with age (p<0.05) occurred and not with BMI and more patients (p<0.05) did not receive analgesics. SBP, DBP, HR changed similarly in both groups at 15, 30 and 45 min. The ECG and SpO2 remained unchanged. CONCLUSIONS Clonidine (4mcg/kg) in epidural anesthesia with ropivacaine 0.75% in hemorrhoidectomy showed safety and greater analgesia within four hours. The pain at 12 hours showed correlation with age and not with body mass index.

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منابع مشابه

[Clinical evaluation of clonidine associated to ropivacaine for epidural anesthesia.].

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Dexmedetomidine and clonidine as an adjuvant to epidural anaesthesia: A prospective randomized, double blind study of their effect on postoperative sensory and motor block characteristics

Background: Many researchers have been done to find an ideal adjuvant to ropivacaine in regional anaesthesia that inhibits intra and post-operative pain and prolong the duration of anaesthesia without any side effects. Aim: This study was conducted to evaluate the onset, extent and duration of sensory and motor block and side effects of clonidine or dexmedetomidine when used as an adjuvant to r...

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A Comparative Study of Qualitative Analgesia for Postoperative Period between Ropivacaine and Ropivacaine with Clonidine in Epidural Block

Background: Pain is one of the most emotional sensation known to mankind. It frequently exceeds its protective nature and makes postoperative period a suffering. The pain in the postoperative period demands relief not only on humanitarian ground but also to reduce physical morbidity following the operation. So relief of pain in postoperative period extends the anaesthesiologists interest beyond...

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Comparison between Epidural Ropivacaine versus Ropivacaine with Clonidine in Patients Undergoing Abdominal Hysterectomy: A Randomized Study

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UNLABELLED On the basis of the determination of minimum local analgesic concentration (MLAC), ropivacaine has been demonstrated to be less potent than bupivacaine during the first stage of labor. In this study we assessed the effect of clonidine on the MLAC of ropivacaine. Seventy-seven parturients of mixed parity requesting epidural analgesia for labor (cervical dilation, 3-7 cm) were included...

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عنوان ژورنال:
  • Acta cirurgica brasileira

دوره 29 3  شماره 

صفحات  -

تاریخ انتشار 2014